Therapeutic strategies targeting immune checkpoints provide bright prospects for the control of infectious and neoplastic diseases in animals even though the diseases are refractory now.

Ticks transmit various pathogens as vectors and the negative impact by poultry red mites are a threat to poultry industry. We try to develop the preventive strategies of these ectoparasites by vaccination.

To date, the number of reported cases of bovine leukemia virus infection tends to increase in cattle in Japan. Our research activities focus on the analysis of the pathogenesis during the infection, and the establishment of the strategy to control the infections in the field.

Marek's disease virus causes a neoplastic disease in chickens. The disease is currently controlled by vaccination. Our research activities focus on the analysis of the pathogenesis and the mechanisms of vaccine-induced protection, and the development of more effective vaccines.